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Like sibling children, they share common heritage (genes) and some structural homology, often appearing to play different roles in regulating biomineralization in various states of health and disease of dentin and bone (Table 2). All bind to and regulate cell differentiation via different factors [81]. They all have numerous repeat sequences, most are charged. To illustrate, we developed a PERLba
988, 95% confidence interval 0.982�C0.994) and greater physical activity (odds ratio 0.999, 95% confidence interval 0.998�C1.000) at the Diabetes Prevention Program Outcomes Study entry, and greater reductions in body mass index (odds ratio 0.75, 95% confidence interval 0.60�C0.94) and waist circumference (odds ratio 0.998, 95% confidence interval 0.996�C1.0) during the Diabetes Prevention Progra
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Pitates of extracts made from transgenic embryos expressing FLAG-tagged Roc1a, Roc1b, or Roc2 proteins from the Roc1a promoter were probed with antibodies that specifically recognize each Cullin (Figure 1A). The data indicate that Roc1a binds Cullins 1?, but not Cul5, that Roc1b binds strongly only to Cul3, and that Roc2 binds only to Cul5. This is consistent with our previous mass spec results [
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