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Genetic alterations in melanoma. N Engl J Med 2005, 353:2135?147. 4. Van Raamsdonk CD, Bezrookove V, Green G, Bauer J, Gaugler L, O'Brien JM, Simpson EM, Barsh GS, Bastian BC: Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature 2009, 457:599?02. 5. Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S, Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, et a
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How these kind of throughout vitro consequences relate to the inside vivo effects of azacitidine therapy remains set up. This is because, we have recently proven which inside vivo and in vitro outcomes of azacitidine may vary. We all observed an average boost in FOXP3-expressing Treg that has a small decrease in IFN�� producing cells in high-risk MDS individuals helped by azacitidine, even though
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